Inhibitory neurons derived from induced pluripotent stem cells
(blue: cell nucleus; red: inhibitory neurotransmitter; green: neuronal marker) [Copyright: Institute of Reconstructive Neurobiology, UK Bonn]
Research
WG Reckzeh - Chemical Biology & Organoids
Prof. Dr. Elena S. Reckzeh
TRA „Life & Health“, Life and Medical Science (LIMES) Institute
University of Bonn
We use stem cell-derived model systems of the gut (organoids, mini-organs) and colon tumors (tumor-organoids) to study extrinsic and intrinsic influences on nutrient uptake, dependence and flexibility. We are especially interested in key regulators mediating metabolic adaptation. We use our organoid models to find new biologically active substances (compounds) to study metabolic phenomena.
Tags: Other Somatic Stem Cells Intestine Stem Cell Niche Organoids Disease Modelling Drug Screening/Discovery Translational Research Cancer Stem Cells
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