WG Tumor Metabolism

Our research group tumor metabolism is focusing on metabolic changes in melanoma cancer cells and stem cells i.a. in patients. We focus on cancer metastasis which is a complex process where cells have to adapt their metabolism in order to survive. We also work with hematopoietic stem cells that are known for the tight regulation of their metabolism esp. during regeneration.

We are using state-of-the-art mass spectrometry to assess metabolic differences in cells. We also use stable isotope tracers to better understand and dissect metabolic fluxes in cells.

Overall, our goal is to gain more insights in cancer metabolism during metastasis to assess metabolic adaptations. We aim to use our metabolic tools to test our findings in other cancer entities and stem cells.