Inhibitory neurons derived from induced pluripotent stem cells
(blue: cell nucleus; red: inhibitory neurotransmitter; green: neuronal marker) [Copyright: Institute of Reconstructive Neurobiology, UK Bonn]
Research
Molecular and genetic toxicology
Prof. Dr. Gerhard Fritz
- Genotoxin-inducible cellular stress responses and cell death
- DNA damage response (DDR) and DNA repair
- Susceptibility of chemical carcinogenesis
- Ras-homologous (Rho) GTPases and tumor progression
- Pharmacological modulation of cytotoxic drugs or radiation to normal tissue
- Mechanisms of organ toxicity
- Regulation of antioxidant factors
Tags: Induced Pluripotent Stem Cells Embryonal Stem Cells Nervous System Heart Liver Lung Kidney Disease Modelling Preclinical Trials Drug Screening/Discovery Biomarker
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