New cell model for the study of brain diseases

05/22/2019   News

Learn more about the innovative and promising model, which consists of a single nerve cell derived from human skin cells.

Nerve Cell

Cell model: A single nerve cell (red) is visible on a layer of astrocytes (blue). Copyright: Dr. Ali Shaib/MPI for Experimental Medicine Göttingen.


Image of a "single" Neuron: The single nerve cell is shown in red, the synapses are coloured in blue. Copyright: Dr. J. Brunner/Vrije Universiteit Amsterdam

Together with working groups from Göttingen and Amsterdam, scientists from the lab of Prof. Oliver Brüstle (University Hospital Bonn (UKB)) developed a new model for the analysis of brain diseases. The new cell model is standardized and scalable and therefore promising for applications in pharmaceutical research. It can be used to analyze and compare signaling in cells from healthy and diseased patients. Interestingly, the model exists of only a single nerve cell derived from human skin cells.

Learn more about this cell “talking to itself" and the scientific details behind it:

Press release of the UKB: A nerve cell serves as a “single” for studies, May 14, 2019

Insights into the research of Professor Oliver Brüstle.