Instead of a poster session, elevator pitches were chosen as contribution and presentation format for the 10th International Meeting.

More than 80 scientists were selected by abstracts and were invited to present their research data in a pre-recorded 3 min elevator pitch. These videos gave a quick overview on the research approach and generated interest for more information. The pitch presenters invested a lot of time in preparing the pitches and it was impressive to see the versatile and creative formats! The corresponding abstract, list of co-authors and a direct contact to the main author were also available next to each pitch.

During the conference there were dedicated “Pitch your research” sessions and pitch presenters were directly available for further questions – similar to a discussion at a poster on a “normal” conference. Additionally, pitch presenters could be contacted at any time during the conference via message or videocall on the conference platform. The pitches are clustered in 7 topics and the videos will stay online at the conference platform until April 30.

The best three pitches were awarded during the final session. The prizes are kindly provided by The International Journal of Biochemistry & Cell Biology!

These are the awardees:

  • Frederike Klaus (1. Place, 500€)
    • Institute of Reconstructive Neurobiology, University of Bonn Medical Faculty & University Hospital Bonn, Germany
    • Pitch title: “The GCNF-BCL11A axis as a regulator of neural stem cell differentiation”
  • Johanna Geuder (shared 2. Place, 200€)
    • Human Genomics and Anthropology, Ludwig-Maximilians University Munich
    • Pitch title: “A non-invasive method to generate induced pluripotent stem cells from primate urine”
  • Sanjana Mathew(shared 2. Place, 200€)
    • University Hospital Würzburg | Chair Tissue Engineering and Regenerative Medicine
    • Pitch title: “Online impedance measurement system in a dynamic flow bioreactor to study barrier integrity of iPSC –based blood brain barrier in vitro models”

Below you find an overview of the Pitches classified by topic in the order of presentation during the "Pitch your research" sessions.

#1: Cell Programming

Author Pitch Title
Lea Jessica Flitsch Converting Microglia into Neural Stem Cells for Neuroregeneration
Ralf Jauch Lineage reprogramming toward induced neural stem cells with re-engineered SOX17
Moyra Lawrence A novel progenitor marker panel pinpoints the biogenesis of the human megakaryocyte progenitor state in vitro and maps its differentiation to human in vivo counterparts.
Harshini Muralidharan Triple negative breast cancer stem cells induce microenvironmental change through stromal cross talk
Pascal Röderer Rapid generation of functional sensory neurons from human IPSC by overexpression of NGN1, BRN3A and ISLET1
Michelle Vincendeau Elevated HERV-K(HML-2) expression negatively impacts human cortical development

#2: Stem Cell Epigenetics

Author Pitch Title
Ledio Bocova Deconvolution of hematopoietic progenitor cells based on DNA methylation profiles
Olivia Cypris Human iPSC lines with knockout of different DNMT3A exons do not acquire de novo DNA methylation during differentiation
Frederike Klaus The GCNF-BCL11A axis as a regulator of neural stem cell differentiation
Harini Narasimhan Role of TNF alpha in the regulation of pro-angiogenic signalling in Triple Negative Breast Cancer
Peter Tessarz Decreased chromatin plasticity of aged MSCs causes loss of their osteogenic potential due to MDV-lysosomal degradation of citrate carrier
Vithurithra Tharmapalan Epigenetic Age is Accelerated in Myeloproliferative Neoplasms

#3: Stem Cells in Regeneration

Author Pitch Title
Ciarra Almeria Hypoxia Conditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Induce Increased Vascular Tube Formation in vitro
Sofia Grade A critical role of the host brain environment in cell-based approaches for restoring brain circuits
Rolf Heumann Cytoplasmic Functionalization and Magnetic Translocation of Nanoparticles Coupled to Ras-Regulating Protein SOS1cat and Guidance of Nanoparticles into Neurite Tips of Induced Human Dopaminergic Neurons
Giada Mantellato Cell death regulation in the hair follicle stem cell niche
Inês Moniz UC-MSC Quiescence: how hypoxia increases the therapeutic value of UC-MSC
Markley Oliveira Junior The corticosteroid medrysone fosters remyelination scaffolded by oligodendrogenesis and, astrocyte heterogeneity on SVZ and corpus callosum.
David Pla Martín Mitochondrial function is essential for cell fate decision of muscle stem cells and proper muscle differentiation
Ignacio Rodríguez Polo Generation of non-human primate iPSCs-derived myocardial cell types for cardiac tissue engineering
Kazuko Schmidt The proliferative effects of blood plasma on human cardiac stem cells are partially mediated by p38 MAPK-signalling

#4: Tissue-specific Stem Cells

Author Pitch Title
Krisitna Bartmann A human iPSC-based in vitro neuronal network formation assay to investigate neurodevelopmental toxicity of pesticides
Saskia Breuel CD44 variant expression and their functional role in breast cancer stem cells from triple negative breast cancer
Sara Di Persio EGR4-dependent UTF1 decrease is associated with failure to reserve spermatogonial stem cells in infertile men
Jessica Dörnen Investigation of (stem cell) characteristics of MSC × breast cancer fusion hybrid cells
Megan Druce The impact of aging, replication and stress of genome stability in hematopoietic stem cells.
Nancy Adriana Espinoza-Sanchez Prognostic significance of hedgehog signaling network-related gene expression in breast cancer patients
Francesca Ferraro IRAK2 depletion renders Breast Cancer Stem Cells (BCSCs) non tumorigenic via differentiation
Martin Götte The heparan sulfate proteoglycan Syndecan-1 and heparanase are novel regulators of colon cancer stem cell function and therapeutic resistance
Martin Götte The Heparan Sulfate Sulfotransferases HS2ST1 and HS3ST2 Are Novel Regulators of Breast Cancer Stem-Cell Properties
Julia Hartmann Optimizing the Neural Induction of Human Induced Pluripotent Stem Cells (hiPSCs) for Application in Toxicological Risk Assessment
Hanna Malyaran Role of periodontal ligament stem cells from the upper and lower jaw on wound healing
Stefan Masjosthusmann Implementation of a human neural progenitor cell based medium throughput screening assay in a developmental neurotoxicity (DNT) testing battery
Sanjana Mathew Online impedance measurement system in a dynamic flow bioreactor to study barrier integrity of iPSC –based blood brain barrier in vitro models
Philipp Joel Mroch Early Events in the COPD Pathogenesis focussed on Basal stem cells
Margaretha A. Skowron Regulation of the stem cell marker CD24 in embryonal carcinomas - the pluripotent non-seminoma stem cell-like population
Lucas-Sebastian Spitzhorn UriCell: Personalized kidney screening platform based on urine-derived renal progenitor cells
Svenja Wein Functional fibrin-based hydrogels for controlling cell/biomaterial interactions in biohybrid implants

#5: Bioengineering, Biomaterials and Microenvironment

Author Pitch Ttitle
Jella-Andrea Abraham NSCs under strain – Unraveling the mechanoprotective role of differentiating astrocytes in a cyclically stretched co-culture with differentiating neurons
Yannik Breitkreuz Towards automating CRISPR/Cas9-based genome editing using the StemCellFactory
Kristin Glotzbach Regulation of neural differentiation by artificial polymers and extracellular matrix-derived peptides
Niraimathi Govindasamy 3D biomimetic implantation niche reveals the first interactions of the embryo and the maternal blood vessels
Julia Kapr Alginate/gellan gum/laminin hydrogel blends for the generation of electrically active 3D neural models
Sebastian Kress Advanced in vitro management of three-dimensional cell cultures and explanted tissue

#6: Disease Modeling and Organoids

Author Pitch Title
Andreea Belu Development of nociceptive signaling in differentiating iPSC-derived nociceptors
Brenda Besemer Modeling inflammasome activation in human iPSC-derived microglia
Yannik Breitkreuz Cytochrome P450 (CYP) activity in standardized and scalable human iPSC-derived cortical spheroids
Maximilian Breyer Analysis of neuronal globotriaosylceramide and ion channel interaction in Fabry disease
Niclas Flosdorf Investigating the impact of JAK2 V617F megakaryocytes on myelofibrosis in an iPS cell model
Nina Graffmann A stem cell based in vitro model of non-alcoholic fatty liver disease enables the analysis of patient specific individual metabolic adaptations in response to a high fat diet and AdipoRon interference
Mohamad Hajo Assessing developmental neurotoxicity and embryonic brain metabolism of paracetamol using human neural progenitor cells
Carla Hartmann An Alzheimer’s disease-specific iPSC-derived blood-brain barrier model to study the role of APOE4
Vira Iefremova Elucidating the role of TSC1 in early corticogenesis using cerebral organoids
Anil Kalia Nav1.7-linked Human Pain: iPSC-derived Sensory Neurons Unravel the Clinical Phenotype of a Patient with Erythromelalgia
Katharina Klug Understanding mechanisms linking Gb3 depositions to endothelial and neuronal pathology in Fabry disease
Sarah Konze GNE myopathy – Why is only muscle affected?
Chao-Chung Kuo DNA Methylation Patterns To Unveil Measurable Residual Disease in Acute Myeloid Leukemia
Mona Mathews Production of iPSC-derived microglia using a developmentally informed protocol
Carmen Maria Menacho Pando Aberrant neuronal activity in Leigh syndrome patient-derived neurons carrying mutations in the mitochondrial complex I gene NDUFS4
Thorsten Müller Characterization of cerebral organoids from human iPS cells with a PSEN1 E280A mutation and ApoE3/4 genotype as a model for Alzheimer’s disease
Lars Roll Neural stem/progenitor cell-associated glycoepitopes in human cerebral organoids
Mareike Sieler Examination of the role of syncytin-1 in cell fusion of breast epithelial cells and breast cancer cells
Marcelo Augusto Szymanski de Toledo Modeling KIT D816V Systemic Mastocytosis with Induced Pluripotent Stem Cells: Identification of Nintedanib as a New Drug Candidate
Fabian M. Troschel Syndecan-1 (SDC-1) influences radioresistance in a 3D breast cancer model

#7: Pluripotent Stem Cells

Author Pitch Title
Mohamed Elsafi Mabrouk Progressive Spatial Self-Organization Of Pluripotent Stem Cell In Colonies And Aggregates
Saskia Galanjuk Characterization of the human induced pluripotent stem cell (HIPS)-test for embryotoxicity assessment
Marina Gattiglio How does cell communication regulate the differentiation of mesoderm subtypes?
Johanna Geuder A non-invasive method to generate induced pluripotent stem cells from primate urine
Boris Greber A resource of clincal-grade human iPS cells with immune compatibility to the caucasian population
Katia Mattis Highly efficient single-cell cloning of human iPSCs in sub-microliter volumes
Dhruv Raina Intermittent ERK oscillations downstream of FGF in mouse embryonic stem cells
Devika S Evolutionarily conserved genes involved in PSM and somites of Mouse and Human
Sina Schumacher Intercellular signaling in embryo-like stem cell aggregates
Smita Sudheer Human ES cell culture conditions fail to preserve the mouse epiblast state
Julia Tigges Academic application of good cell culture practice for induced pluripotent stem cells
Fabian Titz-Teixera Expression kinetics of differentiating mouse embryonic stem cells
Kira Zeevaert YAP knockout suppresses early germ layer specification of human iPSC-derived embryoid bodies